Are you interested in circulating biomarker discovery, basic exosome research or other exosome-realted studies? System Biosciences Exosome Lipidomics & Metabolomics services helps you quickly and efficiently get the most information from your exosomes.
Lipidomics studies of exosomes will identify lipid-based biomarkers and help to understand vesicle biogenesis and function (Subra C, et al. 2007, PMID:17157973). Exosomes carry also a wide range of metabolites that can be used for biomarker discovery as they have been shown to reprogram metabolic machinery upon uptake by cancer cells fueling growth (Zhao H, et al. 2016, PMID:PMC4841778
SBI team has been working with exosomes for years and can reliably and reproducibly isolate exosomes from almost any biofluid such as plasma and tissue culture media, CSF, synovial fluid, and even mouse bronchial alveolar fluid. The sample input requirements are very low. 0.5-1 ml for serum, plasma and ascites fluid, 5-10 ml for cell media, urine and CSF, for other samples please contact us.
You can send your sample or purified exosomes and you will receive a spreadsheet with putative identifications, mass/charge ratios, and diffential analysis (if requested).
In summary
- Discover novel circulating biomarkers
- Learn more about exosome biology
- Send us your sample and receive data in 4–6 weeks
- MS data will be delivered as Excel files with putative identification based on the m/z ratio of the analytes
- Differential analysis of lipids and metabolites between treatment groups will be included in the Excel files