Product description
CALHM1 controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration. It controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca2+ dependent manner. However, no association between CALHM1 and AlzheimerÕs risk is unclear. Member of the FAM26 family of proteins. CALHM1 is predominantly expressed in the adult brain. It has also been detected in retinoic acid-differentiated SH-SY5Y cells. Also colocalizes with HSPA5 at the endoplasmic reticulum.
Specifications
Applications
WB, ELISA
Host
Rabbit
Supplier
Exalpha, an Absolute Biotech Company
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
-20°C

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Calcium Homeostasis Modulator Protein 1

X2410P

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Calcium Homeostasis Modulator Protein 1

X2410P

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