Legenda image
Mouse Anti-Tau Antibody [1D5] used in ICC/IF on Human iPSC-derived neurons (SMC-607)
Product description
Alzheimer’s Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). There are six isoforms of tau in the adult human brain: three with four repeat units (4R) and three with three repeat units (3R) (4). 2N4R, or Tau-441 is the full length tau protein. P301S is a mutation encoded by exon 10 (4) that impairs the ability of tau to assemble microtubules (5).
Specifications
Applications
WB, ELISA, IF, ICC, DB
Host
Mouse
Clonality
Monoclonal
Clone
1D5
Isotype
IgG1
Supplier
Stressmarq
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Mouse Anti-Human Tau Monoclonal IgG, clone 1D5

SMC-607D-APC

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Mouse Anti-Human Tau Monoclonal IgG, clone 1D5

SMC-607D-APC

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