Do you want to use study protein-DNA interaction?

Our supplier Epigentek provides Chromatin Immunoprecipitation Sequencing (ChIP-Seq) Service that is very useful for your research.

ChIP can be used to determine whether a specific protein binds to a particular sequence of a gene, such as the target sequence of a transcription factor or to compare the levels of histone methylation associated with a specific gene promoter region between normal and diseased tissues. Identifying the genetic targets of DNA binding proteins and revealing the mechanism of protein-DNA interaction is crucial for understanding cellular processes.

Map genome-wide histone modifications with EpiGentek’s comprehensive chromatin immunoprecipitation sequencing (ChIP-Seq) platform. Optimized buffers and protocol allow minimal ChIP background and increased sensitivity and specificity of the ChIP reaction.

Highlights

  • Map any H2, H3, H4 histone modifications across the entire genome
  • All kits used in our ChIP-Seq services are commercially available with our ChIP-Seq Workflow.
  • Highly efficient enrichment of targeted DNA. Enrichment ratio of positive to negative control > 500.
  • High sensitivity and flexibility allows both non-barcoded (singleplexed) and barcoded (multiplexed) DNA library preparation.
  • Flexible sample requirements

Delivery of high-quality publishable data (Illumina FASTQ raw sequencing files, FastQC quality control insight, Bismark read mapping, Peak calling, peak annotation and differential binding analysis).