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Anti-LC3 (Human) mAb
M152-3
200 ug
€558
Product description
Macroautophagy mediates the bulk degradation of cytoplasmic components. These components are delivered to lysosomes via autophagosomes. The rat microtubule-associated protein 1 light chain 3 (LC3), a homologue of yeast Atg8 (Aut7/Apg8), localizes to autophagosomal membranes after post-translational modifications. The C-terminal fragment of LC3 is cleaved immediately following synthesis to yield a cytosolic form called LC3-I (18 kDa). A subpopulation of LC3-I is further converted to an autophagosome-associating form, LC3-II (16 kDa). This antibody can detect both forms of LC3.
Specifications
Applications
FC, IP, WB, ICC
Host
Mouse
Clonality
Monoclonal
Clone
4,00E+12
Supplier
MBL International
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C
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Anti-LC3 (Human) mAb
M152-3
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Anti-LC3 (Human) mAb
M152-3
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