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AG-490
J02-901-25
25 mg
Price on request
Product description
A potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently blocked cell growth, induced apoptosis and inhibited DNA synthesis. Blocks the growth of all pre-B ALL cells with no effect on normal B or T cells. Does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src.
Specifications
CAS number
133550-30-8
Supplier
SignalChem
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
20-25°C
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Productname
AG-490
J02-901-25
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