Product description
TOSO/Fas apoptotic inhibitory molecule 3 (FAIM3) was initially identified as an inhibitor for Fas-mediated apoptosis when overexpressed in T cells. The molecule has recently been identified as a Fc receptor for IgM (FcµR) both in humans and mice. FcµR (TOSO/FAIM3) is predominantly expressed in B lymphocyte lineage cells. In humans, FcµR is also expressed on T cells. Chronic lymphocytic leukemia cells are reported to express increased levels of FcµR compared to healthy B cells, and that its expression in the leukemia cells is controlled by B-cell receptor signaling. These observations may suggest a role for FcµR in BCR signaling and/or B-cell activation.
Specifications
Applications
FC
Host
Rat
Clonality
Monoclonal
Clone
4B5
Supplier
MBL International
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Anti-Fc micro R (TOSO/FAIM3) (Mouse) mAb -FITC

D303-4

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Anti-Fc micro R (TOSO/FAIM3) (Mouse) mAb -FITC

D303-4

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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