Product description
Abl interactor (Abi) proteins are c-Abl-binding proteins that bind to both the Src homology 3 (SH3) domain and the C-terminal proline-rich regions of Abl kinase through dual SH3-PXXP interactions. Two highly related genes, abi-1 and abi-2, were cloned. In addition to the interaction with Abl kinase, Abi proteins also interact with other signaling molecules. Recently, it has been reported that Abi-1 dramatically promoted c-Abl-mediated tyrosine (Tyr296) phosphorylation of Mena [mammalian homologue of Drosophila Enabled (Ena)] by interacting with both proteins.
Specifications
Applications
IP, IHC, WB
Host
Mouse
Clonality
Monoclonal
Clone
1B9
Supplier
MBL International
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C

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Anti-Abi-1 (Abl interactor 1) (Human) mAb

D147-3

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Anti-Abi-1 (Abl interactor 1) (Human) mAb

D147-3

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