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Anti-Runx2 (Cbfa1) mAb
D130-3
100 ul
€511
Product description
?Runx2, also known as Cbfa1 or PEBP2?A, is an essential transcription factor of skeletal tissues that is involved in the regulation of osteoblast differentiation and bone formation. Runx2-null mice have neither bone tissue nor osteoblasts. FGF receptor signaling, TGF-?, and BMP all activate transcription of Runx2, resulting in inhibition of myogenesis and myogenic differentiation. BMP-induced Runx2 cooperates with BMP-activated Smads to induce osteogenesis. Runx2 has also been shown to play a role in the regulation of chondrocyte hypertrophy and tooth eruption.
Specifications
Applications
IP, IHC, WB, ELISA, ICC
Host
Mouse
Clonality
Monoclonal
Clone
8G5
Supplier
MBL International
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C
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Anti-Runx2 (Cbfa1) mAb
D130-3
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Anti-Runx2 (Cbfa1) mAb
D130-3
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