Product description
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.
Specifications
Applications
ELISA
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Supplier
CusaBio
Shipping & storage
Storage temperature
-20°C

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Rabbit anti-Human AGO3 Polyclonal Antibody

CSB-PA875700LB01HU-100

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Rabbit anti-Human AGO3 Polyclonal Antibody

CSB-PA875700LB01HU-100

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