Product description
CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells.
Specifications
Applications
FC, IP, IHC-Fr, IF, ICC, FUNC
Host
Hamster
Clonality
Monoclonal
Clone
37.51
Isotype
IgG
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C

Order your product by email

Productname

anti-CD28 antibody (37.51) (Functional Grade)

ARG62796100

By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


Request a sample

Productname

anti-CD28 antibody (37.51) (Functional Grade)

ARG62796100

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


Organization information

*Required fields


Are you looking for specific products, alternatives or documentation?