Product description
CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade, and is expressed mainly by monocytes, macrophages, neutrophils, eosinophils, and mast cells, but also e.g. by hepatocytes, glial cells, vascular endothelial cells, or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response, including superoxide anion production, chemotaxis, and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
S5/1
Isotype
IgG2a
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
2-8°C

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Productname

anti-CD88 / C5AR1 antibody (S5/1) (PE)

ARG54294050

By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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Productname

anti-CD88 / C5AR1 antibody (S5/1) (PE)

ARG54294050

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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