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anti-IL10 antibody (JES3-12G8) (Biotin)
ARG21422100
100 ug
€503
Product description
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Specifications
Applications
IHC-P, IHC-Fr, WB, ELISA
Host
Rat
Clonality
Monoclonal
Clone
JES3-12G8
Isotype
IgG2a, kappa
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
2-8°C
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anti-IL10 antibody (JES3-12G8) (Biotin)
ARG21422100
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Productname
anti-IL10 antibody (JES3-12G8) (Biotin)
ARG21422100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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