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anti-TrkB antibody
ARG20177025
25 ug
€284
Product description
Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting through trkB such as BDNF.
Specifications
Applications
IP, IHC-P, WB, IF, ICC
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C
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anti-TrkB antibody
ARG20177025
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anti-TrkB antibody
ARG20177025
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