Product description
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Specifications
Applications
ELISA
Host
Mouse
Clonality
Monoclonal
Clone
3A6
Isotype
IgG1, kappa
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C

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anti-Insulin antibody (3A6)

ARG10115100

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Productname

anti-Insulin antibody (3A6)

ARG10115100

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