Product description
Rabbit anti p53DINP1 antibody recognizes p53DINP1 (p53-dependent damage-inducible nuclear protein 1). The protein promotes p53 phosphorylation on Ser46 in response to DNA double strand breaks, thereby inducing apoptosis. p53DINP1 is found in the nucleus and is ubiquitously expressed. Expression is dramatically reduced in pancreatic ductal adenocarcinomas early in the development of pancreatic cancer.Two isoforms of the protein exists, a 27kDa alpha and an 18kDa beta form. AHP1659 detects a band of 27kDa in human lung tissue lysate. In human spleen, and mouse liver and kidney tissue a band is detected at 18kDa.
Specifications
Applications
IHC, WB
Host
Rabbit
Clonality
Polyclonal
Supplier
Bio-Rad
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Rabbit Anti-p53DINP1

AHP1659

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Rabbit Anti-p53DINP1

AHP1659

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