Rabbit Anti-Human IL 27 receptor Alpha (C Terminal)

Rabbit anti human IL-27Rα antibody recognizes the carboxy terminal of the alpha subunit of the human IL-27 receptor, otherwise known as the T cell cytokine receptor (TCCR). It is a member of the type I cytokine receptor family with higher levels of expression in CD4+ T cells than in CD8+ T cells. It is a receptor for Interleukin-27 and is involved in the regulation of Th1-type T cells. It also appears to be involved in innate defense mechanisms. It is highly expressed in lymphoid tissue such as spleen, lymph nodes and peripheral blood leukocytes. It is also weakly expressed in tissues such as the heart, brain and lung.