Goat Anti-Human p70S6K (C Terminal)

Goat anti phospho-70S6K antibody recognizes an epitope within the C-terminal (CT) region of human p70S6K, otherwise known as RPS6KB1 or Ribosomal protein S6 kinase beta-1. 70S6K is a serine/threonine kinase which acts upon 40S ribosomal protein S6 to induce protein synthesis, allowing for efficient G1 phase progression.p70S6K is activated following phosphorylation of several sites, in response to hormones, growth factors, mitogenic stimuli and physical exercise, and is a downstream effector in the AKT/mTOR (mammalian target of rapamycin) signalling pathway. p70S6K also acts as a regulator of cell motility, invasion, and cytoskeletal reorganization.