Rabbit Anti-Human 5 HT7 receptor (C Terminal)

Rabbit anti Human 5-HT7 receptor antibodyrecognizes the C-terminal region of the serotonin (5-hydroxytryptamine, 5-HT) receptor 5-HT₇, which belongs to the G-protein coupled receptor superfamily. Serotonin is a neurotransmitter and vasoactive amine which is thought to play a role in various cognitive and behavioural functions including pain, appetite, mood and sleep.Signalling through 5-HT₇ has several effects, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and gastrointestinal tract. Signalling though 5-HT₇ has also been shown to contribute to early T-cell activation.5-HT₇ has been implicated in depression, autism, and other neuropsychiatric disorders.