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Mouse Anti-Human CD54/ICAM-1-UNLB
9441-01
0,1 mg
€138
Product description
CD54, also known as intercellular cell adhesion molecule-1 (ICAM-1), is a 90 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It exhibits a wide tissue distribution being expressed on both hematopoietic and non-hematopoietic cells. ICAM-1 expression on leukocytes is low but is rapidly upregulated upon activation. Expression on endothelium and other non-hematopoietic cells is strongly upregulated by inflammatory mediators. The ligands of CD54 are CD11a/LFA-1? and CD11b/Mac-1?. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels particularly in areas of inflammation. CD54 on antigen-presenting cells (APC) contributes to antigen-specific T cell activation presumably by enhancing interactions between T cells and APC.
Specifications
Applications
FC, IP, IHC, WB, ELISA, ICC
Host
Mouse
Clonality
Monoclonal
Clone
15.2
Isotype
IgG1
Supplier
Southern Biotech
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C
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Mouse Anti-Human CD54/ICAM-1-UNLB
9441-01
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Mouse Anti-Human CD54/ICAM-1-UNLB
9441-01
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