Product description
Integrin ?M (also designated complement component receptor 3 ?-chain; CD11b (p170); macrophage antigen ? polypeptide; cell surface glycoprotein Mac-1 ?-subunit; CR3 ?-chain; MAC1A; MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an ?-chain and a ?-chain. Integrin ?M combines with Integrin ?2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor-1 (Mac-1) or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin ?M-?2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Positive control: Human monocytes and granulocytes. Human lymph node and tonsil.
Specifications
Applications
FC, IHC, ICC
Host
Mouse
Clonality
Monoclonal
Clone
EBS-CD-010
Supplier
PROGEN
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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anti-CD11b mouse monoclonal, EBS-CD-010, purified

691560

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anti-CD11b mouse monoclonal, EBS-CD-010, purified

691560

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