Product description
Mouse anti Human CD227 antibody, clone VU-3C6 recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases.The dominant epitope recognized by this antibody is the 12-mer GVTSAPDTRPAP of the mucin 1 tandem repeat. Mouse anti Human CD227 antibody has been tested on frozen human ovarian carcinoma tissue sections and paraffin embedded sections from normal breast tissue. Mouse anti Human CD227 antibody, clone VU-3C6 also reacts weakly with sections of small intestine and colon.
Specifications
Applications
IP, IHC, WB
Host
Mouse
Clonality
Monoclonal
Clone
VU-3C6
Supplier
Bio-Rad
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Mouse Anti-Human CD227

6378-0135

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Mouse Anti-Human CD227

6378-0135

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