11-Oxoetiocholanolone is a metabolite of cortisol that is found in the feces of ungulates and other animals. Stress-induced glucocorticoids (cortisol, corticosterone) traditionally have been measured through blood sampling, but the collection process is known to cause stress in animals, interfering with experimental results.{19086} Fecal sample analysis provides more accurate detection of stress hormones, and it can be used to measure stress in both laboratory and free-ranging animals.{19086} 11-Oxoetiocholanolone is also found in human urine. Increased levels of urinary 11-oxoetiocholanolone have been observed in the latter part of pregnancy and in patients with uterine leiomyomas.{35076,35077} A study of postmenopausal women determined that 11-oxoetiocholanolone was indicative of stress-induced urinary incontinence.{35075}
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Cayman Chemical
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