Product description

CD45 (leukocyte common antigen), the most common hematopoietic lineage marker, is a transmembrane glycoprotein tyrosine phosphatase with important roles in immune system signal transduction pathways. Antibody panels have been instrumental in identifying multiple isoforms, including CD45RA. Isoforms differ in their extracellular domain and are generated by alternative splicing of exons 4, 5 and 6 encoding peptide segments called A, B, and C, respectively. At least five different isoforms have been identified in humans: containing all three (ABC), two (AB and BC), one (B) or no (O) exons. A given antibody recognizes either every isoform (CD45 antibody) or only a subset (restricted CD45R antibody). The CD45RA 158-4D3 antibody clone reacts with the ABC and BC isoforms. CD45RA has a molecular weight of 205-220 kDa.

Specifications
Applications
FC, IHC-P, WB, IF
Host
Mouse
Clonality
Monoclonal
Clone
158-4D3
Isotype
Mouse IgG2a, kappa
Supplier
Abeomics
Shipping & storage
Storage temperature
-20°C

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Productname

Monoclonal Antibody to CD45RA (Clone: 158-4D3)

36-3014

By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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Productname

Monoclonal Antibody to CD45RA (Clone: 158-4D3)

36-3014

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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