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3-Methylxanthine
34288-25
25 g
€198
Product description
3-Methylxanthine is a cGMP phosphodiesterase (PDE) inhibitor and a metabolite of theophylline (Item No. 23760) and caffeine (Item No. 14118).{60649,60650,60651} It is formed from theophylline by the cytochrome P450 (CYP) isoform CYP1A2 and from caffeine via 6A5NF-1,3-dimethyluracil, 1,3,7-trimethyluric acid, or theobromine intermediates. 3-Methylxanthine inhibits cGMP PDE in isolated guinea pig trachealis muscle with an IC50 value of 920 µM.{60649} It is neurotoxic to mice, inducing convulsions with an ED50 value of 1,107 nmol/kg.{60652}
Specifications
CAS number
1076-22-8
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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34288-25
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