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B-Actin (N-Term) Rabbit Monoclonal Antibody
32127-100
100 uL
€704
Product description
?-Actin is a cytoskeletal protein with roles in cell division, migration, and homeostasis that is encoded by ACTB in humans.{52776,52777} It is ubiquitously expressed, localized to the cytosol, and conserved from birds to mammals. ?-Actin is enriched at the leading edge of migrating cells and Actb-/- mouse embryonic fibroblasts (MEFs) exhibit decreased migration velocity, increased apoptosis, and decreased proliferation.{52776} Actb knockout is early embryonic lethal in mice, indicating that ?-actin is essential for embryonic development. ACTBR183W and ACTBE346K gain-of-function mutations have been found in patients with deafness, developmental mutations, and juvenile-onset dystonia and neutrophil dysfunction, respectively.{52778} Cayman's ?-Actin (N-Term) Rabbit Monoclonal Antibody can be used for chromatin immunoprecipitation (ChIP), immunocytochemistry (ICC), immunohistochemistry (IHC), immunoprecipitation (IP), and Western blot (WB) applications.
Specifications
Applications
IHC, WB, ICC, ChiP
Host
Rabbit
Clone
RM112
Isotype
IgG
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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B-Actin (N-Term) Rabbit Monoclonal Antibody
32127-100
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B-Actin (N-Term) Rabbit Monoclonal Antibody
32127-100
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