APOD GST Recombinant Protein

Source : Escherichia Coli. APO-D Human Recombinant full length protein expressed in E.coli, shows a 48 kDa b& on SDS-PAGE.The APO-D is purified by proprietary chromatographic techniques. Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein &, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure & transport small hydrophobic lig&s. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin & arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes & brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves & in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance & repair within the central & peripheral nervous systems. Apolipoprotein-D is a multi-lig&, multi-functional transporter & transports a lig& from 1 cell to another within an organ, scavenge a lig& within an organ for transport to the blood or could transport a lig& from the circulation to specific cells within a tissue.