APOC1 Recombinant Protein

Source : Escherichia Coli. APOC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 80 amino acids (27-83 a.a.) & having a molecular mass of 9.0kDa. APOC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Apolipoprotein C-I (APOC1) which expressed mainly in the liver is a part of the apolipoprotein C family. APOC1 which is usually found in plasma & responsible for the activation of esterified lechitin cholesterol takes an important part in the exchange of esterified cholesterol among lipoproteins & in removal of cholesterol from tissues. APOC1 is activated when monocytes differentiate into macrophages. APOC1 protein's main role is to inhibit CETP by altering the electric charge of HDL molecules. APOC1 is also binds free fatty acids & reduces their intracellular esterification.