mActivin A Recombinant Protein

Source : E.Coli. Active form Activin-A Murine Recombinant produced in e.coli is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 117 amino acids & having a molecular weight of 26.2kDa.The Active form Activin-A is purified by st&ard chromatographic techniques. Activins are homodimers or heterodimers of the different Beta subunit isoforms, part of the TGF Beta family. Mature Activin A has two 116 amino acids residues BetaA subunits ( BetaA- BetaA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, & reproductive physiology. Activins takes part in the production & regulation of hormones such as FSH, LH, GnRH & ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, & ovarian granulosa cells.