Product description
2’-Deoxyinosine is the nucleoside form of hypoxanthine (Item No. 22254).{59200} It is a product of DNA damage that is formed from 2’-deoxyadenosine (Item No. 27315) by adenosine deaminase or reactive nitrogen species (RNS).{59200,59201} 2’-deoxyinosine (1 mM) enhances apoptosis induced by 5-fluorouracil (5-FU; Item No. 14416) in HT-29 and SW620 cancer cells.{59202} It also enhances 5-FU-induced tumor growth suppression in an SW620 mouse xenograft model when administered at a dose of 1.6 g/kg twice per day.
Specifications
CAS number
890-38-0
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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