JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210 (Item No. 23282).{55163} JKE-1674 reduces viability of LOX-IMVI cancer cells (EC50 = 0.03 uM) and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 (Item No. 17729).
Specifications
Size
5 mg
CAS number
2421119-60-8
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C