DL-Homocysteine is a thiol-containing amino acid derived from methionine.{48974} It inhibits vasodilation of precontracted isolated guinea pig pulmonary artery rings induced by acetylcholine (ACh) and enhances potassium chloride- and phenylephrine-induced contraction of isolated guinea pig pulmonary artery rings.{48975} DL-Homocysteine (200 uM) inhibits endothelium-dependent ACh-induced vasodilation in the vascular bed of isolated perfused rat pancreas.{48976} Elevated plasma levels of DL-homocysteine are positively correlated with occlusive arterial diseases and atherosclerosis.{48974,48975}
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Cayman Chemical
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