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Anti-CD49b / Integrin alpha 2 Monoclonal Antibody (Clone:AK7)
30-1071
0,1 mg
€614
Product description
CD49b / Integrin alpha 2 (ITGA2; alpha 2 subunit of VLA-2) heterodimerizes with CD29 to form the VLA-2 integrin alpha2/beta1 complex, which serves as a receptor for type I collagen, laminin, and E-cadherin. It also acts as a receptor for echovirus. Expressed on platelets, activated lymphocytes, monocytes, fibroblasts, epitelial and endothelial cells, CD49b mediates adhesion of these cells to the extracellular matrix. This interaction supports e.g. T cell proliferation and cytokine production, or wound healing. Defect in CD49b is associated with bleeding disorder platelet-type 9. Antibodies against CD49b are found in several immune disorders, including neonatal alloimmune thrombocytopenia.
Specifications
Applications
FC, IP, IHC-Fr, WB, ELISA, ICC
Host
Mouse
Clonality
Monoclonal
Clone
AK7
Isotype
Mouse IgG1
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C
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Anti-CD49b / Integrin alpha 2 Monoclonal Antibody (Clone:AK7)
30-1071
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Anti-CD49b / Integrin alpha 2 Monoclonal Antibody (Clone:AK7)
30-1071
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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