Rabbit Anti-Bovine collagen I

Rabbit anti Bovine collagen I antibody recognizes bovine collagen type I and cross reacts weakly with human collagen type I. Negligible reactivity has been observed with chicken collagen I, Bovine collagen II, IX and XI and bovine fibronectin.Collagen is located in the extracellular matrix of connective tissues. It is part of the interacting network of proteoglycans and proteins that provides a structural framework for both soft and calcified connective tissues. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis.