Product description
CD146, also known as MCAM (melanoma cell adhesion molecule) or MUC18, is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
P1H12
Isotype
Mouse IgG1
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C

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Anti-Hu CD146 PE

1P-783-T100

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Anti-Hu CD146 PE

1P-783-T100

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