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Anti-Hu CD117 Biotin
1B-586-C100
0,1 mg
€231
Product description
CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
Specifications
Applications
FC, IP, IHC-Fr, ICC
Host
Mouse
Clonality
Monoclonal
Clone
104D2
Isotype
Mouse IgG1 kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD117 Biotin
1B-586-C100
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Anti-Hu CD117 Biotin
1B-586-C100
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