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Anti-Hu CD32 APC
1A-751-T100
100 tests
€283
Product description
CD32 (FcgammaRII) is a low affinity receptor for aggregated IgG. It is strongly expressed on monocytes, granulocytes, myeloid and myeloblastic cell lines, and weakly on B cells, CD34+ bone marrow cells, and resting and activated platelets. After binding its ligand, CD32 induces IgG-mediated phagocytosis and oxidative burst in monocytes and neutrophils, whereas in B cells it mediates a negative signal. This polymorphic transmembrane glycoprotein is expressed not only in the activating (CD32a) and inhibitory isoform (CD32b), but also in individual variants with differing avidities for IgG subtypes (e.g. the CD32a131R and CD32a131H allotypes).
Specifications
Applications
FC
Host
Human
Clone
3D3
Isotype
Mouse IgG1 kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD32 APC
1A-751-T100
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Anti-Hu CD32 APC
1A-751-T100
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