Product description
2-iodomelatonin is a potent agonist of melatonin receptor 1 (MT1; Ki = 28 pM) that is 5-fold selective for MT1 over MT2.{26017,26021} It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin (Item No. 14427) with an EC50 value of 11 pM. 2-iodomelatonin has been used to characterize the role of MT1 in melatonin-mediated signaling.{40764,40765}
Specifications
CAS number
93515-00-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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2-Iodomelatonin

19711-5

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