Product description
Adropin is a 76 amino acid secreted peptide expressed in the brain, liver, and plasma and is encoded by the energy homeostasis associated gene.{16583} It is highly conserved in mammals, and is involved in glucose homeostasis and lipid metabolism.{16583} Plasma levels of adropin decrease with age and have been associated with metabolic disorders such as dyslipidemia and insulin resistance.{21988} Adropin is involved in post-transcriptional activation of eNOS, the up-regulation of VEGFR2, and activation of the ERK1/2 pathway.{21989} Adropin’s involvement in endothelial cells results in increased proliferation and migration, and decreased permeability and apoptosis.{21989} Western blot detects adropin at 14-17 kDa in an over-expression cell lysate, and at 25 kDa for SUMO-tagged adropin recombinant protein.
Specifications
Applications
IHC, WB, ELISA
Host
Mouse
Clonality
Monoclonal
Clone
CC1133F5
Isotype
IgG1
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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Adropin Monoclonal Antibody (Clone CC1133F5)

14117-200

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Productname

Adropin Monoclonal Antibody (Clone CC1133F5)

14117-200

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