Product description
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis.{1642} The precursor form of all caspases is composed of a prodomain and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a tetramer to form the active enzyme. Caspase-1 is similar to the cell death gene CED-3 of C. elegans and regulates multiple proinflammatory cytokines, including interleukin-1? and interferon-?-inducing factor.
Specifications
Applications
IHC-P, WB
Host
Mouse
Clonality
Monoclonal
Clone
14F468
Isotype
IgG1?
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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Caspase-1 Monoclonal Antibody (Clone 14F468)

13907-1

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Productname

Caspase-1 Monoclonal Antibody (Clone 14F468)

13907-1

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