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TRF2 Polyclonal Antibody
13791-1
1 each
€688
Product description
Telomeric repeat binding factor (TRF2) is a ubiquitously expressed protein that is implicated in the control of telomere length.{18142} TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes.{18142} TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini.{18143} The use of mutant forms of TRF2 has implicated a role of TRF2 in the prevention of senescence in primary human cells.{18143} Inhibition of TRF2 results in apoptosis in a subset of mammalian cell types.{18144}
Specifications
Applications
IHC, WB, IF, ICC, ChiP
Host
Goat
Clonality
Polyclonal
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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TRF2 Polyclonal Antibody
13791-1
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TRF2 Polyclonal Antibody
13791-1
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