Toggle Nav
NF-kB (p50) Monoclonal Antibody (Clone 2J10D7)
13755-1
1 each
€778
Product description
NF-?B is a transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis, and inflammation. NF-?B1 (p50), a 50 kDa functional sub-unit of NF-?B, is a member of the Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing a nuclear localization signal, DNA-binding and dimerization domains. NF-?B (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-?B factor. NF-?B (p50) directs the nuclear translocation of NF-?B and is instrumental in its DNA-binding. A pathological role of NF-?B has been suggested in AIDS, hematogenic cancer cell metastasis, and rheumatoid arthritis.
Specifications
Applications
WB
Host
Mouse
Clonality
Monoclonal
Clone
2J10D7
Isotype
IgG1?
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
Do you have any questions about this product?
Order your product by email
Productname
NF-kB (p50) Monoclonal Antibody (Clone 2J10D7)
13755-1
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Request a sample
Productname
NF-kB (p50) Monoclonal Antibody (Clone 2J10D7)
13755-1
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Are you looking for specific products, alternatives or documentation?
