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Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282)
13733-1
1 each
€793
Product description
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer, as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. Akt/PKB phosphorylation is critical for its activity. The major phosphorylation sites required for Akt activation have been identified as threoinine 308 and serine 473. Serine473 is phosphorylated by MAPKAP kinase 2.
Specifications
Applications
IP, WB
Host
Mouse
Clonality
Monoclonal
Clone
104A282
Isotype
IgG2?
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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Productname
Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282)
13733-1
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Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282)
13733-1
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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