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CAY10622
13687-5
5 mg
€331
Product description
Two Rho-associated kinases (ROCK), ROCK1 and ROCK2, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal.{17734,17735,17322} CAY10622 is a potent, ureidobenzamide inhibitor of ROCK1 and ROCK2 with IC50 values of 6 and 4 nM, respectively.{17910} It is inactive (showing greater then 100-fold selectivity) against an additional 44 kinases.{17910}
Specifications
CAS number
1038549-25-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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13687-5
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