2',3',5'-triacetyl-5-Azacytidine

2',3',5'-triacetyl-5-Azacytidine is a prodrug form of the DNA methyltransferase inhibitor 5-azacytidine (Item No. 11164).{67147} It decreases promoter methylation of P15 in L1210 mouse leukemia cells when used at concentrations of 1 and 100 µM. 2',3',5'-triacetyl-5-Azacytidine (10 µM) reduces HIV-1 infection in, and increases the viability of, unstimulated primary human CD4+ T cells.{67146} It decreases gut and spleen global DNA methylation levels in mice when administered at a dose of 38 mg/kg per day for 5 consecutive days.{67147}