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Rosuvastatin
12029-5
5 mg
€69
Product description
Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM).{15309} It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM.{58863} Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet.{58864} It decreases the area of aortic atherosclerotic lesions in the same model. Formulations containing rosuvastatin have been used in the treatment of dyslipidemias.
Specifications
CAS number
287714-41-4
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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Rosuvastatin
12029-5
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