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SUMO Monoclonal Antibody
12021-500
500 ug
€387
Product description
The small ubiquitin like modifier (SUMO) protein is similar in structure and function to ubiquitin. However, SUMO does not typically target proteins for degradation as does ubiquitin.{14288,19512,19511,16072} SUMO is involved with the modification of a very diverse array of targets.{15532} Proteins involved with transcriptional regulation, DNA damage repair, genomic stability, nuclear transport, and histone modification are all subject to modification by SUMO.{19512,15532,19513,15531} SUMO typically functions by covalently binding to a target protein, followed by regulation of protein:protein and protein:DNA interactions.{19512} The SUMO family of proteins is highly conserved from yeast to human. Invertebrates contain a single SUMO gene (Smt3 in yeast and smo-1 in C. elegans), with three members of SUMO being identified in vertebrates to date (SUMO-1, SUMO-2 and SUMO-3).{21733}
Specifications
Applications
WB, ELISA
Host
Mouse
Clonality
Monoclonal
Clone
3B5
Isotype
IgG1
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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SUMO Monoclonal Antibody
12021-500
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SUMO Monoclonal Antibody
12021-500
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