Product description
CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
Specifications
Applications
FC, IHC-Fr, WB, FUNC
Host
Mouse
Clonality
Monoclonal
Clone
ITEM-4
Isotype
Mouse IgG2b
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C

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Anti-Hu CD266 Purified Low Endotoxin

12-755-C100

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Anti-Hu CD266 Purified Low Endotoxin

12-755-C100

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