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Anti-Hu CD279 Purified Low Endotoxin
12-176-C100
0,1 mg
€167
Product description
CD279 / PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its receptors CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis.
Specifications
Applications
FC, IHC-Fr, FUNC
Host
Mouse
Clonality
Monoclonal
Clone
EH12.2H7
Isotype
Mouse IgG1 kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD279 Purified Low Endotoxin
12-176-C100
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Anti-Hu CD279 Purified Low Endotoxin
12-176-C100
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