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Anti-Hu CD137 Purified Low Endotoxin
12-143-C100
0,1 mg
€167
Product description
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
Specifications
Applications
FC, IP, ELISA, FUNC
Host
Mouse
Clonality
Monoclonal
Clone
4B4-1
Isotype
Mouse IgG1 kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD137 Purified Low Endotoxin
12-143-C100
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Anti-Hu CD137 Purified Low Endotoxin
12-143-C100
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